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Abr . 26, 2025 11:32 Back to list

HPMC CAS Number Technical Data for Construction & Pharma



  • Introduction to HPMC CAS Number and Its Significance
  • Technical Advantages of HPMC-Based Compounds
  • Performance Comparison of Leading HPMC Manufacturers
  • Custom Solutions for Industry-Specific Needs
  • Real-World Applications and Case Studies
  • Regulatory Compliance and Safety Standards
  • Future Trends in HPMC CAS 9002-89-5 Utilization

hpmc cas number

(hpmc cas number)


Understanding HPMC CAS Number and Its Industrial Relevance

Hydroxypropyl methylcellulose (HPMC), identified by CAS number 9004-65-3, serves as a critical polymer across pharmaceuticals, construction, and food production. With a global market growth rate of 6.8% CAGR (2023-2030), this cellulose derivative outperforms alternatives like polyvinyl alcohol (CAS 9002-89-5) in thermal stability and biodegradability. Manufacturers prioritize HPMC’s CAS registration to ensure material traceability and compliance with REACH/EPA standards.

Technical Superiority in Polymer Formulations

HPMC demonstrates 15-20% higher viscosity retention compared to standard methylcellulose variants under extreme pH conditions (2-12). Key metrics include:

  • Gelation temperature range: 50-90°C (adjustable per substitution grade)
  • Moisture retention capacity: 72% at 25°C/60% RH
  • Ash content: ≤1.5% (pharma-grade specifications)

Market Leaders in HPMC Production

Manufacturer Viscosity Range (mPa·s) Purity (%) Certifications
Dow Chemical 5-200,000 99.8 USP, EP, FDA
Shin-Etsu 10-150,000 99.5 JPE, ISO 9001
Ashland 15-100,000 99.2 Halal, Kosher

Tailored Solutions for Sector-Specific Challenges

Construction-grade HPMC (CAS 9004-65-3) modifies cement hydration rates by 18-22%, reducing crack formation in mortars. Pharmaceutical applications leverage its delayed-release properties, achieving 94-97% API encapsulation efficiency in tablet coatings. Customizable parameters include:

  • Particle size distribution: 20-200 μm
  • Methoxy/propylene oxide content ratios
  • Dissolution rates (immediate to 24-hour release)

Documented Success in Commercial Projects

A 2022 infrastructure project in Germany utilized 12 tons of HPMC (viscosity 40,000 mPa·s) to enhance adhesive mortar performance. Results showed:

  • 38% reduction in water absorption
  • 27% improvement in freeze-thaw resistance
  • Project cost savings: €156,000 over PVA alternatives

Compliance with International Quality Frameworks

HPMC meets stringent regulatory requirements, including:

  • EP 10.0 Monograph 04/2013:1472
  • FDA 21 CFR §172.874
  • ISO 20795-1:2013 (Dental applications)

Why HPMC CAS 9004-65-3 Dominates Advanced Material Science

With 83% of pharmaceutical formulators preferring HPMC over PVA (CAS 9002-89-5) for film-coating applications, its molecular flexibility enables precise control over drug release profiles. Ongoing R&D focuses on:

  • Nanocellulose composites (18-22 nm particle size)
  • Temperature-responsive hydrogels
  • Bioadhesive formulations with 95% mucosal retention

hpmc cas number

(hpmc cas number)


FAQS on hpmc cas number

Q: What is the CAS number for HPMC?

A: The CAS number for Hydroxypropyl Methylcellulose (HPMC) is 9004-65-3. It is a cellulose-derived polymer used in pharmaceuticals, food, and construction.

Q: What is the CAS number for Polyvinyl Alcohol (PVA)?

A: The CAS number for Polyvinyl Alcohol is 9002-89-5. It is a water-soluble synthetic polymer commonly used in adhesives, coatings, and packaging.

Q: Is CAS 9002-89-5 related to HPMC or PVA?

A: CAS 9002-89-5 refers specifically to Polyvinyl Alcohol (PVA), not HPMC. HPMC has a distinct CAS number: 9004-65-3.

Q: How do I differentiate HPMC and PVA using CAS numbers?

A: HPMC is identified by CAS 9004-65-3, while PVA uses CAS 9002-89-5. These numbers ensure accurate chemical identification in regulatory documents.

Q: Why is CAS 9002-89-5 sometimes confused with HPMC?

A: Confusion arises because both HPMC and PVA (CAS 9002-89-5) are polymers used in similar industries. Always verify CAS numbers to avoid misidentification.


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